Johan Larsson, Christian Rück and David Mataix-Cols just landed a smash (sorry for the badminton joke) with a new study published in European Neuropsychopharmacology where a group of patients with severe OCD that had been treted with neurosurgery were studied. Results show that symptoms in the symmetry/ordering domain were associated with greater severity of OCD, depression and anxiety, as well as greater impairment at follow-up. The results challenge our current conceptualization of OCD as a unitary diagnostic entity with a single neurobiological substrate. Read more here:
Rück C, Larsson K.J., Mataix-Cols D. Predictors of medium and long-term outcome following capsulotomy for Obsessive-Compulsive Disorder: One site may not fit all. European Neuropsychopharmacology. 2011 Dec 29. [Epub ahead of print]. PMID: 2220936215.