58. Gajecki M, Berman AH, Sinadinovic K, Andersson C, Ljótsson B, Hedman E, Rück C, Lindefors N. Effects of baseline problematic alcohol and drug use on internet-based cognitive behavioral therapy outcomes for depression, panic disorder and social anxiety disorder. PLoS One. 2014 Aug 14;9(8):e104615. doi: 10.1371/journal.pone.0104615. eCollection 2014.

57. Andersson E, Ljótsson B, Hedman E, Hesser H, Enander J, Kaldo V, Andersson G, Lindefors N, Rück C. Testing the Mediating Effects of Obsessive Beliefs in Internet-Based Cognitive Behaviour Therapy for Obsessive-Compulsive Disorder: Results from a Randomized Controlled Trial. Clin Psychol Psychother. 2014 Nov 23. doi: 10.1002/cpp.1931. [Epub ahead of print]

56. Hedman E, Andersson G, Lindefors N, Gustavsson P, Lekander M, Rück C, Andersson E, Ljótsson B.Personality Change following Internet-Based Cognitive Behavior Therapy for Severe Health Anxiety. PLoS One. 2014 Dec 1;9(12):e113871. doi: 10.1371/journal.pone.0113871. eCollection 2014.

55. Vidal-Ribas P, Stringaris A, Rück C, Serlachius E, Lichtenstein P, Mataix-Cols D. Are stressful life events causally related to the severity of obsessive-compulsive symptoms? A monozygotic twin difference study. Eur Psychiatry. 2014 Dec 12. pii: S0924-9338(14)00649-X. doi: 10.1016/j.eurpsy.2014.11.008. [

54. Cederlöf M, Lichtenstein P, Larsson H, Boman M, Rück C, Landén M, Mataix-Cols D. Obsessive-Compulsive Disorder, Psychosis, and Bipolarity: A Longitudinal Cohort and Multigenerational Family Study. Schizophr Bull (2014) doi: 10.1093/schbul/sbu169

53. Andersson E, Hedman E, Ljótsson B, Wikström M, Elveling E, Lindefors N,
Andersson G, Kaldo V, Rück C. Cost-effectiveness of internet-based
cognitive behavior therapy for obsessive-compulsive disorder: Results from
a randomized controlled trial (in press) Journal of Obsessive-Compulsive
and Related Disorders

52. Isomura K, Boman M, Rück C, Serlachius E, Larsson H, Lichtenstein P, Mataix-Cols D.Population-based, multi-generational family clustering study of social anxiety disorder and avoidant personality disorder. Psychol Med. 2014 Sep 12:1-9.

51. Enander, J., Ivanov, V., Andersson, Mataix-Cols, D., Ljótsson, B., Rück, C. (In Press). Therapist-guided Internet-based Cognitive Behavioral Therapy for Body Dysmorphic Disorder (BDD-NET): A Feasibility Study. BMJ Open.

50. Valerie Voon, Laurel Morris, Mike Irvine, Christian Rück, Yulia Worbe, Katherine Derbyshire, Vladan Rankov, Liana Schreiber, Brian Odlaug, Neil Harrison, Jonathan Wood, Trevor Robbins, Ed Bullmore, and Jon Grant. (In press). Risk taking in disorders of natural and drug rewards: neural correlates and effects of probability, valence and magnitude. Neuropsychopharmacology.

49. Hedman, E., El Alaoui, S., Lindefors, N., Andersson, E., Rück, C., Ghaderi, A., Kaldo, V., Lekander, M., Andersson, G., & Ljótsson, B. (In press). Clinical effectiveness and cost-effectiveness of Internet- vs. group-based cognitive behavior therapy for social anxiety disorder: 4-year follow-up of a randomized trial. Behaviour Research and Therapy.

48. Schibbye, P., Ghaderi, A., Ljótsson, B., Hedman, E., Lindefors, N., Rück, C., & Kaldo, V. (In press). Using Early Change to Predict Outcome in Cognitive Behaviour Therapy: Exploring Timeframe, Calculation Method, and Differences of Disorder-Specific versus General Measures. PLOS ONE

47. Lenhard F, Vigerland S, Andersson E, Rück C, Mataix-Cols D, et al. (2014) Internet-Delivered Cognitive Behavior Therapy for Adolescents with Obsessive-Compulsive Disorder: An Open Trial. PLoS ONE 9(6): e100773. doi:10.1371/journal.pone.0100773

46. Tiger M, Rück C, Forsberg A, Varrone A, Lindefors N, Halldin C, Farde L, Lundberg J.  Reduced 5-HT1B receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder. (In Press). Psychiatry Research: Neuroimaging.

45. Hedman E, Lekander M, Ljótsson B, Lindefors N, Rück C, Hofmann SG, Andersson E, Andersson G, Schulz SM. Sudden gains in internet-based cognitive behaviour therapy for severe health anxiety. Behav Res Ther. 2014 Mar;54:22-9. doi: 10.1016/j.brat.2013.12.007. Epub 2014 Jan 11.

44. Gentil AF, Lopes AC, Dougherty DD, Rück C, Mataix-Cols D, Lukacs TL, Canteras MM, Eskandar EN, Larsson KJ, Hoexter MQ, Batistuzzo MC, Greenberg BD, Miguel EC. Hoarding symptoms and prediction of poor response to limbic system surgery for treatment-refractory obsessive-compulsive disorder. J Neurosurg. 2014 Apr 4. [Epub ahead of print]

43. . Voon V, Derbyshire K, Rück C, Irvine MA, Worbe Y, Enander J, Schreiber LR, Gillan C, Fineberg NA, Sahakian BJ, Robbins TW, Harrison NA, Wood J, Daw ND, Dayan P, Grant JE, Bullmore ET. Disorders of compulsivity: a common bias towards learning habits. Mol Psychiatry. 2014 May 20. doi: 10.1038/mp.2014.44

42. Andersson, E., Steneby, S., Karlsson, K., Ljótsson, B., Hedman, E., Enander, J., Kaldo, V., Andersson, G., Lindefors, N., Rück, C. (in press) Long-term efficacy of Internet-based cognitive behavior therapy for obsessive-compulsive disorder with or without booster: A randomized controlled trial. Psychological Medicine

41. Hedman E, Ljótsson B, Kaldo V, Hesser H, El Alaoui S, Kraepelien M, Andersson E, Rück C, Svanborg C, Andersson G, Lindefors N.Effectiveness of Internet-based cognitive behaviour therapy for depression in routine psychiatric care. J Affect Disord. 2014 Feb;155:49-58. doi: 10.1016/j.jad.2013.10.023.


40: Hedman, E., Ljótsson, B., Blom, K., El Alaoui, S., Kraepelien, M., Rück, C., Andersson, G., Svanborg, C., Lindefors, N., & Kaldo, V. (2013). Telephone vs. Internet -administration of self-report measures of social anxiety, depressive symptoms, and insomnia: validation of a method to reduce the impact of missing data.  J Med Internet Res. 2013 Oct 18;15(10):e229. doi: 10.2196/jmir.2818.

39. El Alaoui, S., Hedman, E., Ljótsson, B., Bergström, J., Andersson, E., Rück, C., Andersson, G. & Lindefors, N. Predictors and Moderators of Internet- and Group-based Cognitive Behaviour Therapy for Panic Disorder. PLoS One. 2013 Nov 7;8(11):e79024. doi: 10.1371/journal.pone.0079024.

38. Evelyn Andersson, Christian Rück, Catharina Lavebratt, Erik Hedman, Martin Schalling, Nils Lindefors, Elias Eriksson,Per Carlbring, Gerhard Andersson& Tomas Furmark. Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder
PLoS One. 2013 Nov 15;8(11):e79015. doi: 10.1371/journal.pone.0079015.

37. Hedman E, Andersson E, Andersson G, Lindefors N, Lekander M, Rück C, Ljótsson B. (2013) Mediators in Internet-Based Cognitive Behavior Therapy for Severe Health Anxiety. PLoS ONE 8(10): e77752. doi:10.1371/journal.pone.0077752

36. Hedman E, Lindefors N, Andersson G, Andersson E, Lekander M, Rück C, Ljótsson B. Predictors of outcome in Internet-based cognitive behavior therapy for severe health anxiety. Behav Res Ther. 2013 Oct;51(10):711-7. doi: 10.1016/j.brat.2013.07.009. Epub 2013 Aug 11.

35: Ivanov VZ, Mataix-Cols D, Serlachius E, Lichtenstein P, Anckarsäter H, Chang Z, Hellner Gumpert C, Lundström S, Långström N, Rück C. (2013) Prevalence, Comorbidity and Heritability of Hoarding Symptoms in Adolescence: A Population Based Twin Study in 15-Year Olds. PLoS ONE 8(7): e69140.

34. Ljótsson B, Hesser H, Andersson E, Lindfors P, Hursti T, Rück C, Lindefors N, Andersson G, Hedman E. Mechanisms of Change in an Exposure-Based Treatment for Irritable Bowel Syndrome. J Consult Clin Psychol. 2013 Dec;81(6):1113-26. doi: 10.1037/a0033439.

33. David Mataix-Cols, PhD; Marcus Boman, BSc; Benedetta Monzani, MSc; Christian Rück, MD; Eva Serlachius, MD; Niklas Långström, MD; Paul Lichtenstein, PhD. Population-Based, Multigenerational Family Clustering Study of Obsessive-Compulsive Disorder. JAMA Psychiatry. 2013;():1-9.

32. Hedman, E., Ljótsson, B., Rück, C., Bergström, J., Andersson, G., Kaldo, V., Jansson, L., Andersson, E., Andersson, E., Blom, K., El Alaoui, S., Falk, L., Ivarsson, J., Nasri, B., Rydh, S., & Lindefors, N. Effectiveness of Internet-based cognitive behaviour therapy for panic disorder in routine psychiatric care. Acta Psychiatr Scand. 2013 Feb 14. doi: 10.1111/acps.12079.

31. E. Hedman, E. Andersson, N. Lindefors, G. Andersson, C. Rück and B. Ljótsson (2013). Cost-effectiveness and long-term effectiveness of Internet-based cognitive behaviour therapy for severe health anxiety. Psychological Medicine, 43, pp 363-374. doi:10.1017/S0033291712001079.


30. Enander J., Andersson E., Kaldo V., Lindefors N., Andersson G., Rück C. Internet administration of the Dimensional Obsessive-Compulsive Scale: a psychometric evaluation. Journal of Obsessive-Compulsive and Related Disorders. 2012 Volume: 1   Issue: 4   Pages: 325-330

29. Cervenka, S., Hedman, E., Ikoma, Y., Radu Djurfeldt, D., Rück, C., Halldin, C., Lindefors, N. Changes in dopamine D2-receptor binding are associated to symptom reduction after psychotherapy in social anxiety disorder. Translational Psychiatry. Translational Psychiatry (2012) 2, e120; doi:10.1038/tp.2012.40
Published online 22 May 2012

28. Ljung R, Rück C, Mattsson F, Sjöberg Bexelius T, Lagergren J, Lindblad M. Selective serotonin receptor blockers and risk of acute pancreatitis – a Swedish population-based case-control study. J Clin Psychopharmacology. 2012 Apr 26. [Epub ahead of print] PMID: 22544014

27.  Andersson E, Enander J, Andrén P, Hedman E, Ljótsson B, Hursti T, Bergström J, Kaldo V, Lindefors N, Andersson G, Rück C. Internet-based cognitive behaviour therapy for obsessive–compulsive disorder: a randomized controlled trial. Psychological Medicine, Psychol Med. 2012 Oct;42(10):2193-203 Available on CJO doi:10.1017/S0033291712000244

26. Hedman, E., Andersson, E., Ljótsson, B., Andersson, G., Andersson, E., Schalling, M., Lindefors, N. and Rück, C. (2012), Clinical and genetic outcome determinants of Internet- and group-based cognitive behavior therapy for social anxiety disorder. Acta Psychiatrica Scandinavica. doi: 10.1111/j.1600-0447.2012.01834.x


25. Andersson, E., Walén, C., Hallberg, J., Paxling, B., Dahlin, M., Almlöv,
J., Källström, R., Wijma K, Carlbring P, Andersson G. A randomized controlled trial of guided Internet-delivered cognitive behavioral therapy for erectile dysfunction. J Sex Med. 2011 Oct;8(10):2800-9, PMID: 2800­2809.

24. Rück C, Larsson K.J., Mataix-Cols D. Predictors of medium and long-term outcome following capsulotomy for Obsessive-Compulsive Disorder: One site may not fit all. European Neuropsychopharmacology. 2011 Dec 29. [Epub ahead of print]. PMID: 2220936215.

23. Ljótsson B, Andersson G, Andersson E, Hedman E, Lindfors P, Andréewitch S, Rück C, Lindefors N. Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: a randomized controlled trial. BMC Gastroenterol. 2011 Oct 12;11:110. PMID: 21992655

22. Hedman E, Andersson EM, Ljótsson B, Andersson G, Rück C & Lindefors N. Cost-effectiveness of Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: results from a randomized controlled trial. Behav Res Ther 2011 Nov;49(11):729-36. PMID: 21851929

21. Andersson EM, Ljótsson B, Hedman E, Kaldo V, Paxling B, Andersson G, Lindefors N and Rück C. Internet-based cognitive behavior therapy for obsessive compulsive disorder: A pilot study. BMC Psychiatry 2011, 11:125. PMID:21812991

20. Andersson E, Ljótsson B, Smit F, Paxling B, Hedman E, Lindefors N, Andersson G, Rück C. Cost-effectiveness of internet-based cognitive behavior therapy for irritable bowel syndrome: results from a randomized controlled trial. BMC Public Health. 2011 Apr 7;11:215. PMID: 21473754

19. Hedman E, Furmark T, Carlbring P, Ljótsson B, Rück C, Lindefors N, Andersson G. A 5-Year Follow-up of Internet-Based Cognitive Behavior Therapy for Social Anxiety Disorder. J Med Internet Res. 2011 Jun 15;13(2):e39 PMID:21676694

18. Ljótsson B, Hedman E, Andersson E, Hesser H, Lindfors P, Hursti T, Rydh S, Rück C, Lindefors N, Andersson G. Internet-Delivered Exposure-Based Treatment vs. Stress Management for Irritable Bowel Syndrome: A Randomized Trial. Am J Gastroenterol 2011 Aug;106(8):1481-91. PMID: 21537360

17. Hedman E, Andersson G, Ljótsson B, Andersson E, Rück C, Mörtberg E, Lindefors N. Internet-based cogntive behavior therapy vs. Cognitive behavioral group therapy for social anxiety disorder: A randomized controlled non-inferiority trial. PLoS ONE 2011 Mar 25;6(3):e18001. PMID: 21483704

16. Hedman E, Andersson G, Andersson E, Ljótsson B, Rück C, Asmundson GJ, Lindefors N. Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trial. Br J Psychiatry. 2011 Mar;198:230-6. PMID: 21357882

15. Ljótsson B, Hedman E, Lindfors P, Hursti T, Lindefors N, Andersson G, Rück C. Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndrome. Behav Res Ther. 2011 Jan;49(1):58-61 PMID: 21092934


14. Hedman E, Ljótsson B, Andersson E, Rück C, Andersson G, Lindefors N. Effectiveness and cost offset analysis of group CBT for hypochondriasis delivered in a psychiatric setting: an open trial. Cogn Behav Ther. 2010 Dec;39(4):239-50. PMID: 20972912

13. Lonsdorf TB, Rück C, Bergström J, Andersson G, Ohman A, Lindefors N, Schalling M. The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder. BMC Psychiatry. 2010 Nov 26;10:99. PMID: 21110842

12. Hedman E, Ljótsson B, Rück C, Furmark T, Carlbring P, Lindefors N, Andersson G. Internet administration of self-report measures commonly used in research on social anxiety disorder: A psychometric evaluation. Computers in Human Behavior 2010; 26: 736-40. DOI: 10.1016/j.chb.2010.01.010

11. Bergström J, Andersson G, Ljótsson B, Rück C, Andréewitch S, Karlsson A, Carlbring P, Andersson E, Lindefors N. Internet-versus group-administered cognitive behaviour therapy for panic disorder in a psychiatric setting: a randomised trial. BMC Psychiatry. 2010 Jul 2;10:54. PMID: 20598127

10. Ljótsson B, Falk L, Vesterlund AW, Hedman E, Lindfors P, Rück C, Hursti T, Andréewitch S, Jansson L, Lindefors N, Andersson G.Internet-delivered exposure and mindfulness based therapy for irritable bowel syndrome–a randomized controlled trial. Behav Res Ther. 2010 Jun;48(6):531-9. PMID: 21092934

9. Rück C, Edman G. Self-rated versus family-rated personality in patients undergoing capsulotomy for obsessive-compulsive disorder. Nord J Psychiatry. 2010 Aug;64(4):239-44. PMID: 20085434

8. Ljótsson B, Andréewitch S, Hedman E, Rück C, Andersson G, Lindefors N.Exposure and mindfulness based therapy for irritable bowel syndrome – An open pilot study. J Behav Ther Exp Psychiatry. 2010 Sep;41(3):185-90. PMID: 20362976


7. Lonsdorf TB, Rück C, Bergström J, Andersson G, Öhman A, Schalling M, Lindefors N. The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Nov 13;33(8):1479-83. PMID:19683026

6. Bergström J, Andersson G, Karlsson A, Andréewitch S, Rück C, Carlbring P, Lindefors N. An open study of the effectiveness of Internet treatment for panic disorder delivered in a psychiatric setting. Nord J Psychiatry. 2009;63(1):44-50. PMID: 18985514


5. Rück C, Karlsson A, Steele JD, Edman G, Meyerson BA, Ericson K, Nyman H, Åsberg M, Svanborg P. Capsulotomy for Obsessive-Compulsive Disorder – long-term follow-up of 25 patients. Arch Gen Psychiatry, 2008 Aug;65(8):914-21 PMID: 18678796

- 2007:

4. Kakko J, Grönbladh L, Svanborg KD, von Wachenfeldt J, Rück C, Rawlings B, Nilsson LH, Heilig M. A stepped care strategy using buprenorphine and methadone versus conventional methadone maintenance in heroin dependence: a randomized controlled trial. Am J Psychiatry. 2007 May;164(5):797-803. PMID: 17475739

3. Rück C, Edman G, Åsberg M, Svanborg P, Long-term Changes in Self-reported Personality following Capsulotomy in Anxiety patients. Nord J Psychiatry 2006;60(6):486-91 PMID: 17162457

2. Rück C, Svanborg P, Meyerson BA. Lesion topography in capsulotomy for refractory anxiety–is the right side the right side? Stereotact Funct Neurosurg. 2005;83(4):172-9. PMID: 16319521

1. Rück C, Andréewitch S, Flyckt K, Edman G, Nyman H, Meyerson BA, Lippitz BE, Hindmarsh T, Svanborg P, Mindus P, Åsberg M: Capsulotomy for refractory anxiety disorders – A long-term follow-up of 26 patients. Am J Psychiatry ; March 2003; 160: 513-521. PMID: 12611833

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  1. Pingback: Rücklab: summing up our first year | The Rück Research Lab

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