CAPRI Kick Off

On 27-28 August, members of CAPRI came together for two inspiring and productive days focused on research, team-building activities and planning for the work ahead.

The programme included presentations from some of the CAPRI members:
– 𝗝𝗼𝗵𝗻 𝗪𝗮𝗹𝗹𝗲𝗿𝘁 – Is it possible to conduct an RCT with involuntary psychiatric inpatients?
– 𝗘𝗹𝗶𝗻 𝗦𝗸𝗼𝘁𝘁 – Widely implemented – incompletely proven?
– 𝗦𝗮𝗻𝗱𝗿𝗮 𝗧𝗮𝗺𝗺 – Conducting research in inpatient care – challenges and how to overcome them
– 𝗝𝗼𝗵𝗮𝗻 𝗕𝗷𝘂𝗿𝗲𝗯𝗲𝗿𝗴 – Who attempts, who dies? thinking about proxies in suicide research

We were also very pleased to welcome Professor 𝗛𝗲𝗹𝗲𝗻 𝗞𝗶𝗹𝗹𝗮𝘀𝗽𝘆, from University College London, who is a new member of CAPRI’s Scientific Advisory Board, who gave a keynote on how research can influence policy for our target group. Moreover, we also had the pleasure to listen to 𝗠𝗶𝗰𝗵𝗮𝗲𝗹 𝗜𝗼𝗮𝗻𝗻𝗼𝘂, who presented the Swedish Psychiatric Association’s ongoing work on guidelines for inpatient care.

Other highlights included a presentation by CAPRI’s Scientific Advisory Board, and another by 𝗩𝗶𝗰𝘁𝗼𝗿 𝗟𝗶𝗻𝗱𝗳𝗼𝗿𝘀, Head of SLSO’s new psychosis clinic, presenting the work he has been involved in with 𝗖𝗮𝗿𝗹 𝗦𝗲𝗹𝗹𝗴𝗿𝗲𝗻 and others to develop a new psychosis clinic.

Overall, the two days were both productive and enjoyable, giving us time to reflect on our work, develop new ideas and make concrete plans for moving forward together.

𝗔𝗯𝗼𝘂𝘁 𝗖𝗔𝗣𝗥𝗜:
Centre for Applied Psychiatric Research and Innovation (CAPRI) is a research centre at the Karolinska Institute focused on improving care for individuals with severe psychiatric conditions treated in high-intensity settings such as inpatient psychiatry, compulsory care, emergency psychiatry, and intensive outpatient programs. CAPRI works to co-develop, evaluate, and implement person-centred interventions together with patients, clinicians, relatives, and social services, with the aim of improving outcomes, reducing coercion and self-harm, strengthening recovery, and informing policy and clinical practice.

𝗖𝗵𝗿𝗶𝘀𝘁𝗶𝗮𝗻 𝗥𝘂𝗰𝗸 is the Director of CAPRI and the center is supported by a Scientific Advisory Board, consisting of 𝗟𝗼𝗿𝗲𝗻𝗮 𝗙𝗲𝗿𝗻𝗮𝗻𝗱𝗲𝘇 𝗱𝗲 𝗹𝗮 𝗖𝗿𝘂𝘇, 𝗣𝗮𝘂𝗹 𝗟𝗶𝗰𝗵𝘁𝗲𝗻𝘀𝘁𝗲𝗶𝗻, 𝗛𝗲𝗹𝗲𝗻 𝗞𝗶𝗹𝗹𝗮𝘀𝗽𝘆 and 𝗗𝗮𝘃𝗶𝗱 𝗠𝗮𝘁𝗮𝗶𝘅 𝗖𝗼𝗹𝘀. 𝗟𝗶𝘀𝗮 𝗚𝘂𝗻𝗻𝗮𝗿𝘀𝘀𝗼𝗻 is the Central Coordinator for CAPRI. Read more about CAPRI here: https://lnkd.in/dki9ZJmu

Lisa Gunnarsson Continues in the Rücklab as a PhD Student!

We are pleased to announce that Lisa Gunnarsson was been appointed PhD student in March, after two years as a Research Assistant in the Rücklab. Lisa holds an M.Sc. by Research in Psychiatry from Oxford University.

Her PhD project addresses two critical gaps in suicide research. First, her research evaluates Brief Cognitive Behavioral Therapy (BCBT) as a suicide-preventive intervention for patients in psychiatric inpatient care in Sweden, a group at exceptionally high risk of suicide following discharge. Second, she will investigate the validity of suicide classifications in the Swedish Cause of Death Register.

Her main supervisor is Christian Rück, and her co-supervisors are Fredrik Johansson and Lorena Fernández de la Cruz. We are very happy that she is continuing as part of our group! 🎉

Olly nailing it!

August 19th, Olly nailed her thesis “Predicting health and socioeconomic outcomes in patients with common psychiatric disorders” in Flemingsberg. 

There was a great turnout from Rücklab group members.

We look forward to her disputation on September 11th!

Hur kan vi tillsammans utveckla framtidens psykiatriska heldygnsvård?


Arbetar du inom psykiatrisk heldygnsvård eller bedriver forskning inom området? Är du beslutsfattare eller representerar en brukarorganisation? Då är du välkommen till en nationell hearing för att diskutera framtidens psykiatriska heldygnsvård den 20 oktober 2026. Vi hoppas att du vill delta och bidra med dina erfarenheter och perspektiv i diskussionen om framtidens heldygnsvård.

Vad: Nationell hearing om psykiatrisk heldygnsvård, arrangerad av CAPRI.
När: 20 oktober 2026, kl. 11.00–16.00.
Var: Stockholm (plats meddelas senare).
Arrangör: Dagen arrangeras av Centrum för tillämpad psykiatrisk forskning och innovation (CAPRI). CAPRI är ett forskningscentrum på Karolinska Institutet som arbetar för att stärka kunskapen om vård för personer med svåra psykiatriska tillstånd.

Beskrivning av hearingen
Syftet är att samla kliniker av alla professioner, forskare, beslutsfattare och brukarorganisationer för att identifiera de viktigaste kunskapsluckorna i heldygnsvården, samt diskutera vilken ny kunskap som kan förbättra vården. Hearingen är en del av CAPRIs arbete med att stärka vården för personer med svåra psykiatriska tillstånd genom att utveckla kunskap om psykiatrisk heldygnsvård och skapa ett underlag för framtida forskningsprioriteringar.

Anmäl dig genom att besvara följande enkät: https://lnkd.in/dyW6-y44
Om du föredrar att anmäla dig via e-post går det bra att mejla penny.taka@ki.se. Deltagandet är kostnadsfritt. Om du tidigare anmält intresse kommer vi höra av oss.

Can Machine Learning Predict Who Benefits From Internet-Delivered CBT?

The latest publication from Rücklab is a new article first-authored by PhD student Olly Kravchenko, with Ralf Kuja-Halkola, Christian Rück, and John Wallert among the co-authors. The study was published in the Journal of Medical Internet Research.

The study investigated whether machine learning can help predict, before treatment begins, which patients are likely to experience clinically meaningful improvement from internet-delivered cognitive behavioural therapy (ICBT) for depression, panic disorder, and social anxiety disorder. Using data from 1,790 patients, the researchers combined clinical and sociodemographic information with data from national registers and genetics to develop and validate several predictive models.

Models incorporating register data performed better than a simpler model based on screening data alone, while genetic polygenic scores did not provide additional predictive value. The findings are a promising step towards tools that could help identify patients who may need more tailored support from the outset. The next step is prospective validation in new patients.

Congratulations to Olly and all co-authors!

Read the full article: https://www.jmir.org/2026/1/e100162

Save the date: en hearing om vad som är bra psykiatrisk heldygnsvård

Hej!
Arbetar du inom psykiatrisk heldygnsvård, bedriver forskning inom området, är beslutsfattare eller representerar du en brukarorganisation?

Välkommen till en 𝗻𝗮𝘁𝗶𝗼𝗻𝗲𝗹𝗹 𝗵𝗲𝗮𝗿𝗶𝗻𝗴 om svensk psykiatrisk heldygnsvård som anordnas den 𝟮𝟬 𝗼𝗸𝘁𝗼𝗯𝗲𝗿 𝟮𝟬𝟮𝟲. Detta är en save the date inför dagen, och vi hoppas att du vill delta och bidra med din kunskap och erfarenhet.

Vad? Nationell hearing om psykiatrisk heldygnsvård, arrangerad av CAPRI och Forte.

När? 20 oktober 2026, kl. 11.00–16.00.

Var? Stockholm (plats meddelas senare).

För vem? Kliniker av alla professioner, forskare, beslutsfattare och brukarorganisationer.

Arrangör: Dagen arrangeras av Centrum för tillämpad psykiatrisk forskning och innovation (CAPRI). CAPRI är ett forskningscentrum som arbetar för att stärka kunskapen om vård för personer med svåra psykiatriska tillstånd och utveckla insatser för högintensiva vårdmiljöer som heldygnsvård. Läs mer här: CAPRI

Beskrivning av hearingen

Syftet är att samla kliniker av alla professioner, forskare, beslutsfattare och brukarorganisationer för att identifiera de viktigaste utmaningarna i heldygnsvården, samt diskutera vilken ny kunskap som  kan förbättra vården.

Hearingen är en del av CAPRIs arbete med att stärka vården för personer med svåra psykiatriska tillstånd genom att utveckla kunskap om psykiatrisk heldygnsvård och skapa ett underlag för framtida forskningsprioriteringar. 

En formell inbjudan med program och praktisk information skickas ut i augusti. Vi hoppas att du har möjlighet att reservera dagen och ser fram emot att träffa dig i Stockholm den 20 oktober.

Här kan du lägga in din mail för att försäkra dig om att få inbjudan: Registrera din e-post för inbjudan här. Vid eventuella frågor, hör gärna av dig till Penny Taka på penny.taka@ki.se

Vänliga hälsningar,

Christian Rück

John Wallert on prediction models in Medicinsk Vetenskap

In the latest issue of Medicinsk Vetenskap 2/2026, John Wallert is interviewed about how our prediction models and AI-based tools can contribute to more accurate risk assessments in healthcare. The article highlights how our ongoing research based on large-scale registry data can support clinicians in identifying patients at increased risk, thereby creating better opportunities for early, equitable and preventive interventions.

Course launch for the third edition of Artificial Intelligence in Mental Healthcare

For the third time, the course Artificial Intelligence in Mental Healthcare is being offered, once again bringing together participants from all over the world to explore one of the most timely and relevant areas in healthcare.

The course takes as its starting point the question of who tomorrow’s clinician will be: human, machine or a combination of both? With a focus on clinical psychology and psychiatry, the course explores how artificial intelligence can be understood, developed and used to support care tailored to each individual patient.

Participants will engage with theory, current research and real-world examples in areas such as chatbots, suicide prediction and applied machine learning. Ethical issues play a central role, as do practical workshops where participants can deepen their understanding of methods and applications. We look forward to welcoming a new group of participants to this year’s course!

CAPRI Track 3 kick-off!

Today we gathered for a full-day kick-off for CAPRI Track 3. CAPRI (Centre for Applied Psychiatric Research and Innovation) is a KI research centre led by Christian Rück focusing on patients with severe psychiatric conditions in high-intensity care settings, aiming to co-create, test, and implement person-centred interventions together with patients, clinicians, and other partners.

During the day we focused on aligning priorities and turning ideas into concrete next steps—ranging from validating and improving risk prediction/decision support tools, to exploring multi-modal AI (e.g., face/voice) as a potential future clinical support, and mapping what we should measure in inpatient settings so that data collection becomes meaningful and actionable. Throughout the day, our track lead John Wallert guided the discussions and also presented the CARE-FORCE trial. Great conversations followed on how cross-disciplinary collaboration can maximise impact. Thanks to everyone who contributed—lots of energy, sharp ideas, and great inspiration!

Guest speaker: Roland Paulsen

Today our research group meeting had the honor of welcoming Roland Paulsen as a guest speaker. He gave an interesting talk on the sociology of risk, which was attended and enjoyed by representatives from numerous research groups. If you would like to know more about Roland’s work, you can find his website here.

Thank you, Roland, for sharing the important work that you are doing!