A new study on risk factors at birth associated with developing OCD later has just been published in JAMA Psychiatry. Over 2 million children were followed and we studied perinatal data from the Swedish Medical Birth Register and included maternal smoking during pregnancy, labor presentation, obstetric delivery, gestational age (for preterm birth), birth weight, birth weight in relation to gestational age, 5-minute Apgar score, and head circumference. A range of perinatal risk factors were associated with a higher risk for OCD independent of shared familial confounders, suggesting that perinatal risk factors may be in the causal pathway to OCD.
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Brander G, Rydell M, Kuja-Halkola R, Fernández de la Cruz L, Lichtenstein P, Serlachius E, Rück C, Almqvist C, D’Onofrio BM, Larsson H, Mataix-Cols D. Association of Perinatal Risk Factors With Obsessive-Compulsive Disorder: A Population-Based Birth Cohort, Sibling Control Study. JAMA Psychiatry. Published online October 05, 2016. doi:10.1001/jamapsychiatry.2016.2095