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Category: News
The first study to present the prevalence comorbidity and heritability of hoarding in adolescents just came out in PLoS ONE. In this study, we report that 2% of Swedish 15-year olds report symptoms of hoarding including distress and/or impairment. This is quite surprising given that hoarding is considered to be a problem most common among the elderly. We also found that hoarding seldom co-occurs with OCD which supports the status of Hoarding Disorder, which has been separated from Obsessive-Compulsive Disorder in the new DSM-5. Finally, using the twin design we were able to conclude that hoarding symptoms are heritable during adolescence but only in boys. In girls, the environment, both the shared, and non-shared between twins accounted for the variability in hoarding symptoms.
Our research group has been collaborating with the Swedish Twin Registry and Professor David Mataix-Cols on this paper and this partnership is only at its start. Keep following us to see what the incredible Swedish Twin data will tell us in the future!
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069140
Ivanov VZ, Mataix-Cols D, Serlachius E, Lichtenstein P, Anckarsäter H, Chang Z, Hellner Gumpert C, Lundström S, Långström N, Rück C. (2013) Prevalence, Comorbidity and Heritability of Hoarding Symptoms in Adolescence: A Population Based Twin Study in 15-Year Olds. PLoS ONE 8(7): e69140.
In a new study that is just out in the Journal of Consulting and Clinical Psychology, researchers led by Brjánn Ljótsson studied how different possible mechanisms of CBT contributed to its efficacy in Irritable Bowel Syndrome. We used parallel process growth mediational analyses (!) to study weekly ratings of gastrointestinal symptom-specific anxiety (GSA) and stress reactivity. Results showed that only GSA displayed a pattern consistent with a causal model in which change in process preceded and contributed to symptom change.
This week, Volen Ivanov vistited Columbia University/New York State Psychiatric Institute to meet with some of Rücklabs favourite OCD researchers and present some of our lab’s recent work on Hoarding Disorder. Big thanks to Dr. Carolyn Rodriguez and Dr. Helen Blair Simpson for having him over! Follow us on Rücklab for some very interesting podcasts on OCD and related disorders coming out soon!
Historic day. #DSM5 just landed in the mail.
A new paper is out using Swedish multigenerational register data showing that the risk for OCD among relatives of OCD probands increased proportionally to the degree of genetic relatedness. Also, partners of people diagnosed with OCD were more likely to have OCD.
David Mataix-Cols, PhD; Marcus Boman, BSc; Benedetta Monzani, MSc; Christian Rück, MD; Eva Serlachius, MD; Niklas Långström, MD; Paul Lichtenstein, PhD. Population-Based, Multigenerational Family Clustering Study of Obsessive-Compulsive Disorder. JAMA Psychiatry. 2013;():1-9.
http://archpsyc.jamanetwork.com/article.aspx?articleid=1689532
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Rücklab’s Evelyn Andersson visited Department of Psychiatry at UCSD last week who hosts prominent researchers such as prof. Hagop Akiskal, famous for his extensive work on mood disorders and prof. John Kelsoe, a pioneer in investigating molecular genetics and bipolar disorder for over 20 years.
Our new Thermo Scientific Formas 88000 series freezer entered service yesterday with Prof Nils Lindefors cutting the red ribbon. The freezer now contains DNA of about 1500 individuals treated with internetbased-CBT and to a lesser extent RNA and plasma.
Erik Andersson has been awarded a grant from the Bror Gadelius memorial fund for our D-cycloserine study in OCD. Who was Bror Gadelius? Well, for someone working on a thesis on OCD like Erik Andersson it is interesting to know that Bror Gadelius, once a leading Swedish psychiatrist born in 1862 wrote his thesis on obsessions (Om Tvångstankar och dermed beslägtade fenomen) in 1896. Gadelius became a professor at Karolinska Institutet in 1903 and worked hard to reform mental health care including bringing psychiatric wards to the main hospitals instead of more remote asylums.
Rücklab - Psychiatry research at Karolinska Institutet 
