Long Long Chen’s dissertation

Last Friday, Long Long Chen successfully defended his thesis Obsessive-Compulsive Disorder – Novel Insights on Executive Functions, Gut Microbiome, and genetics.

Long Long is a specialist in psychiatry, senior specialist at the OCD program at Psykiatri Sydväst, as well as research colleague in the Rück group.

The thesis underlines the fact that Obsessive-Compulsive disorder (OCD) is complex and that it is difficult to identify biological markers as an explanatory model. However, genetic research towards patients with severe and treatment-resistant OCD is promising.

Congratulations, Long Long! 🎺🎺🎺

Genetics in patients with severe treatment refractory OCD – Grant to Long Chen

Research group member Long Chen recently received a grant from the Bror Gadelius memorial fund for his project about genetics in patients with severe treatment refractory obsessive-compulsive disorder (OCD).

The purpose of the study is to accurately map unusual genetic variations in patients with severe treatment refractory OCD. This will be executed by using whole exome sequencing, a method where the protein-coding parts of the gene (the exome) is sequenced. The aim is also to study wether unusual genetic variations have any predictive value for treatment outcomes after deep brain stimulation (DBS), a method that has been shown to benefit patients that are not helped by the current evidence-based medical and psychotherapeutic treatment methods.