New pilot study on acceptance-based exposure therapy for Body Dysmorhic Disorder (BDD)

In a collaboration between Karolinska Institutet and Stockholm University led by Johanna Linde, a pilot study on an acceptance-based approach to BDD has just been published in Behavior Therapy. Highlights included:

  • Pilot study examined the treatment outcomes and feasibility of acceptance-based exposure therapy for BDD in 21 patients
  • At post-treatment, symptoms of BDD, depression, psychological flexibility, quality of life and general functioning were significantly improved
  • Dropout was low, and treatment gains were maintained at 6 months follow-up

These findings need to be confirmed by a controlled study before clinically inplemented.

Linde, J., Rück, C., Bjureberg, J., Ivanov, V. Z., Radu Djurfeldt, D., & Ramnerö.  Acceptance-based exposure therapy for body dysmorphic disorder: A pilot study. Behav Ther. 2015 Jul;46(4):423-31. doi: 10.1016/j.beth.2015.05.002.

New study: Validity of tic and OCD diagnoses in Swedish registers

The usefulness of cases diagnosed in registers for research purposes is dependent on diagnostic validity. This new study aimed to investigate the validity  of recorded diagnoses of tic disorders and obsessive-compulsive disorder (OCD) in the Swedish National Patient Register (NPR). 100 tic disorder cases and 100 OCD cases were randomly selected from the NPR based on codes from the International Classification of Diseases (ICD) 8th, 9th and 10th editions, together with 50 epilepsy and 50 depression control cases. The obtained psychiatric records were blindly assessed by 2 senior psychiatrists according to the criteria of the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) and ICD-10.

Results Between 1969 and 2009, the NPR included 7286 tic disorder and 24 757 OCD cases. The vast majority (91.3% of tic cases and 80.1% of OCD cases) are coded with the most recent ICD version (ICD-10). For tic disorders, the PPV was high across all ICD versions (PPV=89% in ICD-8, 86% in ICD-9 and 97% in ICD-10). For OCD, only ICD-10 codes had high validity (PPV=91–96%). None of the epilepsy or depression control cases were wrongly diagnosed as having tic disorders or OCD, respectively. Inter-rater reliability was outstanding for both tic disorders (κ=1) and OCD (κ=0.98).

Conclusions The validity and reliability of ICD codes for tic disorders and OCD in the Swedish NPR is generally high. We propose simple algorithms to further increase the confidence in the validity of these codes for epidemiological research.

Read the full text here

Rück C., Larsson K.J., Lind K., Perez-Virgil A., Isomura K., Sariaslan A., Lichtenstein P., Mataix-Cols D. Validity and reliability of chronic tic disorder and obsessive-compulsive disorder diagnoses in the Swedish National Patient Register. BMJ Open. 2015 Jun 22;5(6):e007520. doi: 10.1136/bmjopen-2014-007520

Conferment ceremony for Erik Andersson

Karolinska Institutet held its traditional Conferment ceremony for doctoral students. The ceremony took place in the Blue Hall of Stockholm City Hall was followed by a banquet in the Golden Hall and dance. Erik Andersson was promoted to PhD, as symbolized by putting on a funny hat.

Anyway, we congratulate Erik to this achivement! You are the best!

Erik getting his hat
“Yeah, I did it. Can you believe it?”
Erik Andersson and his superproud ex-supervisor Christian Rück
Party like it is promovering, man.

Last stop on the trip in California


Chia-Ying Chou is a postdoc in professor Carol Mathews’s research group at the University of California, San Francisco. She is also a part of the largest clinical trial on Hoarding Disorder to date. Volen got the chance to follow her work with indivudals with hoarding closely and learn some important points on treatment for hoarding. Our lab’s treamtent study for hoarding is just around the corner and we are sure that all the new insights from this trip to California will be beneficial for our coming study participants.

Thank you Carol and Chia-Ying!

Treatment for hoarding in San Francisco

mha sfdb

We at Rück Lab are in the planning stages of a treatment study on Hoarding Disorder, the first in Sweden. In preparation for this, we are meeting up with professionals in California with experience helping people with hoarding. David Bain works at the Mental Health Association of San Francisco and is also a part of a large clinical trial on group treatment for Hoarding Disorder. Dave was generous enough to share his vast experience of hoarding treatment and how it can be delivered effectively. Thank you for being so welcoming and sharing with us Dave!

Rück Lab in California

task force sa

Volen is in California this week, meeting with professionals involved in hoarding task forces and treatment of Hoarding Disorder in and around San Francisco. Below are two members of the relatively new task force in Santa Clara, Dana Girard and Mallory von Kugelgen. A fruitful discussion which led to new ideas about what a Swedish task force could focus on.

It is obvious that there is a lot to be done for people with Hoarding Disorder in Sweden, and that collaboration across organizations is key, More updates from the trip to come.


Group retreat at Hesselby Slott

We just finished a retreat for our group. We were honored that Jim Crowley and Christopher Lalima, Hofstra University had flown in for the meeting.

Erik Hedman gave a fantastic talk on how to write an insane amount of great papers in no time.
Erik Hedman gave a fantastic talk on how to write an insane amount of great papers in no time.
The group.
The group.
Deep discussions.
Deep discussions.
Chris showed us how to sing, really.
Chris showed us how to sing, really.

Man of the day: Gustaf Brander

Gustaf Brander is the latest PhD student to join the battle agianst OCD, or in this particular case, to identify risk factors for OCD. He is a psychologist by training and Prof David Mataix-Cols is his main supervisor and Eva Serlachius and Christian Rück co-supervisors.

I love research!
I just love research!

Half-time seminar Jesper Enander

When? January 16,  13:00
Where? Askö, M56, Karolinska Universitetssjukhuset, Huddinge

Title: Etiology, prevalence, and development of a novel treatment for body dysmorphic disorder

Main supervisor: Christian Rück

Co-supervisors: Paul Lichtenstein, David Mataix-Cols, Brjánn Ljótsson 

Examination board: Bo Melin, Jerker Hetta, Klaas Wijma