Increased risk of suicide in patients with obsessive-compulsive disorder

title Fernández de la Cruz et al

In a recent study published in Molecular Psychiatry, members of our group and colleagues at Karolinska Institutet have looked at suicide in obsessive-compulsive disorder (OCD). The study compared rates of suicide among 36 788 patients with OCD and matched controls without an OCD diagnosis.

The risk of dying by suicide was found to be about 10 times higher in patients with OCD (OR = 9.83 (95% CI, 8.72-11.08). Patients with OCD were also about 5 times more likely to attempt suicide (OR = 5.45 (05% CI, 5.24-5.67). The risk was marginally attenuated in women compared to men.

Lorena Fernández de la Cruz and her co-authors also note that the increased risk of death by suicide

“… remained substantial after adjusting for different groups of psychiatric comorbidities that are already known to be associated with suicide. In fact, 43% of the individuals from the OCD cohort who died by suicide did not have any other recorded psychiatric comorbidity.” (p. 4)

They argue that OCD is associated with an increased risk of death by suicide in its own right. The main predictor for dying by suicide was a previous suicide attempt.

The message for clinicians is clear:

“OCD should be added to the list of psychiatric disorders that are known to increase the risk of suicide in their own right. Suicide risk needs to be carefully monitored in these patients, particularly in those who have previously attempted suicide.” (p. 6)

The paper is freely available here.



2014 in review: highlights

Dear friends,

2014 has been a good year. We have contributed to 18 publications, presented at several congresses, Evelyn Andersson and Volen Ivanov have had their half-time seminars on their steady way to a PhD and Erik Andersson was the first out of our lab to defend his thesis. We have also staged what may be the Worlds first blind breaking party. On a more serious note, several of our treatment studies have helped people who suffer. We have published the first internetbased CBT study for Body Dysmorhic Disorder with Jesper Enander as first author and stay tuned for more on BDD in 2015. We hope to do even more in 2015. If you wish to donate to our research to make it possible, contact .

Oh yeah, he did it. Erik Andersson, PhD, being admired by Sabine Wilhelm and Christian Rück.
Oh yeah, he did it. Erik Andersson, PhD, being admired by Sabine Wilhelm and Christian Rück.
Skärmavbild 2014-03-18 kl. 10.25.05
Volen Ivanov in one of 2014’s many media appearences.


Evelyn Andersson at her half-time seminar
Evelyn Andersson at her half-time seminar

Vi söker en psykolog för banbrytande forskning och klinik

Vår forskningsgrupp söker i samarbete med Mottagningen för Tvångssyndrom, Psykiatri Sydväst en psykolog för att driva vidare forskningen kring internetbaserad KBT för OCD. Behandlingen har redan testats med god effekt i flera studier men vi vill nu göra en studie där iKBT jämförs med individuell KBT i klinik. Tjänsten är en kombinerad forsknings/kliniktjänst där kliniktjänstgöringen är på Mottagningen för Tvångssyndrom, en mottagning som just nu är inne i en expansiv fas. I forskningsdelen handleds du av Dr. Erik Andersson, Docent Christian Rück och Professor David Mataix-Cols. Detta är, för att uttrycka det ödmjukt, en chans att delta i den absoluta framkanten och om allt går bra så är en doktorandtjänst en senare möjlighet.

Läs mer:

On the radio: Om sjukligt samlande i P1

Idag talade bl a Volen Ivanov, Christian Rück och David Mataix-Cols som sjukligt samlande (hoarding) i P1:s Kropp och Själ som du kan lyssna på här:

Även HSB:s psykosociala enhet med Sylvia Mårtensson och Christina Ahlström berättar om deras fantastiska verksamhet i programmet.